Description

[5-(2,2,2-Trifluoro-1,1-Dimethyl-Ethyl)-Isoxazol-3-Yl]-Carbamic Acid Phenyl Ester is a specialized fluorinated isoxazole derivative, serving as a high-value synthetic intermediate in advanced organic chemistry. Its core value lies in the unique trifluoromethylated tert-butyl moiety, which imparts significant metabolic stability and lipophilicity, making it a critical building block for bioactive molecule development. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and fine-tuning the properties of complex molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Serves as a core scaffold for developing next-generation herbicides, fungicides, and insecticides with enhanced efficacy and environmental profile.
• Chemical Biology Probe: Used in medicinal chemistry to study enzyme inhibition and receptor-ligand interactions due to its distinct fluorine pattern.
• Material Science: Potential monomer or additive for creating specialty polymers with unique surface properties and chemical resistance.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring fluorinated heterocycles.

Basic Information

Item	Details
Product Name	[5-(2,2,2-Trifluoro-1,1-Dimethyl-Ethyl)-Isoxazol-3-Yl]-Carbamic Acid Phenyl Ester
CAS No.	1188911-77-4
Molecular Formula	C14H13F3N2O3
Molecular Weight	314.26 g/mol
Synonyms	Phenyl N-[5-(2,2,2-trifluoro-1,1-dimethylethyl)-1,2-oxazol-3-yl]carbamate; Carbamic acid, N-[5-(2,2,2-trifluoro-1,1-dimethylethyl)-3-isoxazolyl]-, phenyl ester; 3-Isoxazolecarbamic acid, 5-(2,2,2-trifluoro-1,1-dimethylethyl)-, phenyl ester; 5-(1,1,1-Trifluoro-2-methylpropan-2-yl)isoxazol-3-yl carbamate phenyl ester; 1188911-77-4; TFMP-Isoxazole Carbamate Phenyl Ester.
EINECS	Contact for details

Quality Control

Our [5-(2,2,2-Trifluoro-1,1-Dimethyl-Ethyl)-Isoxazol-3-Yl]-Carbamic Acid Phenyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.