Description

4-Hydroxy-3-Isopropylphenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides requiring specific phenolic-boronate structures.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLEDs and conductive polymers, where precise molecular assembly is required.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of molecular probes and sensors.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for custom synthesis houses and CROs/CMOs working on client-specific, complex organic molecules.

Basic Information

Item	Details
Product Name	4-Hydroxy-3-Isopropylphenylboronic Acid Pinacol Ester
CAS No.	1188335-75-2
Molecular Formula	C15H23BO3
Molecular Weight	262.15 g/mol
Synonyms	3-Isopropyl-4-hydroxyphenylboronic Acid Pinacol Ester; 4-Hydroxy-3-(1-methylethyl)benzeneboronic Acid Pinacol Ester; (4-Hydroxy-3-isopropylphenyl)boronic Acid Pinacol Ester; 2-(4-Hydroxy-3-isopropylphenyl)-5,5-dimethyl-1,3,2-dioxaborinane; Pinacol (4-Hydroxy-3-isopropylphenyl)boronate
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-3-Isopropylphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We adhere to cGMP principles where applicable to support our customers in regulated industry segments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.