Description

Diosbulbin I CAS NO 1187951-05-8 is a high-purity, bioactive diterpenoid compound isolated from *Dioscorea* species. This compound is of significant interest for its role as a key reference standard and active pharmaceutical ingredient (API) intermediate in advanced research and development. It is primarily sought by professionals in the pharmaceutical, biotechnology, and phytochemical sectors for applications in pharmacological studies, analytical method development, and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of herbal extracts and finished products in quality control laboratories.
• Bioactivity Research: Serves as a critical compound in pharmacological studies investigating anti-inflammatory, hepatoprotective, or anti-cancer mechanisms.
• Natural Product Isolation & Purification: Acts as a benchmark for the isolation, identification, and purification of related diterpenoids from complex botanical matrices.
• Analytical Method Development: Essential for developing and validating HPLC, LC-MS, and other chromatographic methods in analytical R&D.
• API Intermediate Synthesis: Utilized as a building block or precursor in the synthetic pathways for novel drug candidates.
• Nutraceutical Standardization: Employed to standardize and authenticate botanical dietary supplements derived from *Dioscorea*.

Basic Information

Product Name	Diosbulbin I
CAS No.	1187951-05-8
Molecular Formula	C20H24O6
Molecular Weight	360.40 g/mol
Synonyms	Diosbulbin I; (4bS,5S,6aS,9S,10aS,10bS)-5-(Acetyloxy)-4b,5,6,6a,9,10,10a,10b-octahydro-9-hydroxy-4b,7,7,10a-tetramethyl-2H-naphtho[2,1-b]pyran-2-one; 8,9-Epoxy-14,15-dinorlabda-12-ene; A compound from Dioscorea bulbifera
EINECS	Contact for details

Quality Control

Our Diosbulbin I is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity confirmation, IR and MS for structural identification, and residual solvent analysis. We provide a comprehensive Certificate of Analysis (COA) with each shipment, detailing all test results and confirming compliance with in-house specifications developed for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep the container sealed to protect the light-sensitive compound from degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.