Description

(S)-2,2,2-Trifluoro-1-(3-Fluorophenyl)Ethanamine is a high-value chiral amine building block characterized by its trifluoromethyl and fluorophenyl substituents, which are critical for modulating the physicochemical and metabolic properties of target molecules. This compound is essential for research and development in advanced pharmaceutical chemistry, where its unique fluorine pattern is leveraged to enhance drug potency, stability, and bioavailability. It is primarily sought after by medicinal chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the fluorine atoms contribute to improved lipophilicity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and advanced materials with specific fluorinated properties.
• Diagnostic Agent Precursor: Potential building block for fluorinated contrast agents or probes used in imaging technologies like PET (Positron Emission Tomography).

Basic Information

Product Name	(S)-2,2,2-Trifluoro-1-(3-Fluorophenyl)Ethanamine
CAS No.	1187931-53-8
Molecular Formula	C8H7F4N
Molecular Weight	193.14 g/mol
Synonyms	(S)-1-(3-Fluorophenyl)-2,2,2-trifluoroethanamine; (S)-α-(Trifluoromethyl)-3-fluorobenzeneethanamine; (S)-3-Fluoro-α-(trifluoromethyl)benzylamine; (S)-1-(3-Fluorophenyl)-2,2,2-trifluoroethylamine; (S)-2,2,2-Trifluoro-1-(3-fluorophenyl)ethylamine; (S)-TFMPEA; (S)-3-Fluorophenyl trifluoroethyl amine
EINECS	Contact for details

Quality Control

Our (S)-2,2,2-Trifluoro-1-(3-Fluorophenyl)Ethanamine is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.