Description

1-(4-Amino-3-Bromo-Phenyl)-Ethanone Hydrochloride is a high-purity, halogenated aromatic ketone hydrochloride salt, serving as a critical building block in advanced organic synthesis. Its value lies in providing a reactive amino and bromo-substituted aromatic core, enabling precise molecular construction for complex target molecules. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in heterocyclic chemistry for potential CNS, anti-inflammatory, or anti-infective agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging its halogen and amino functionality for bioactivity.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers, dyes, and photoactive materials.
• Chemical Biology & Proteomics: Employed as a scaffold or linker in the design of molecular probes, enzyme inhibitors, and bioconjugation reagents.
• Academic & R&D Laboratories: A versatile reagent for methodological studies in organic chemistry, including cross-coupling and amination reactions.

Basic Information

Product Name	1-(4-Amino-3-Bromo-Phenyl)-Ethanone Hydrochloride
CAS No.	1187927-06-5
Molecular Formula	C8H9BrClNO
Molecular Weight	250.52 g/mol
Synonyms	1-(4-Amino-3-bromophenyl)ethanone hydrochloride; 3'-Bromo-4'-aminoacetophenone hydrochloride; 4'-Amino-3'-bromoacetophenone HCl; 1-Acetyl-4-amino-3-bromobenzene hydrochloride; 3-Bromo-4-aminoacetophenone hydrochloride; 4-Acetamido-2-bromobenzene hydrochloride (tautomeric form); p-Amino-m-bromoacetophenone hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(4-Amino-3-Bromo-Phenyl)-Ethanone Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.