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2-Phenylimidazo[1,2-A]Pyridine-6-Boronic Acid CAS NO 1187822-25-8


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CAS No.:1187822-25-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Phenylimidazo[1,2-A]Pyridine-6-Boronic Acid is a high-value boronic acid derivative and a key synthetic intermediate in modern organic chemistry. Its primary value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and advanced materials.

Application

  • Pharmaceutical Intermediate: A critical building block for synthesizing novel drug candidates, especially in kinase inhibitor and central nervous system (CNS) drug discovery programs.
  • Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with enhanced efficacy.
  • Material Science: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
  • Chemical Research: A versatile reagent in academic and industrial R&D labs for constructing complex heterocyclic scaffolds and exploring new catalytic processes.
  • Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name 2-Phenylimidazo[1,2-A]Pyridine-6-Boronic Acid
CAS No. 1187822-25-8
Molecular Formula C₁₃H₁₁BN₂O₂
Molecular Weight 238.05 g/mol
Synonyms 2-Phenylimidazo[1,2-a]pyridine-6-boronic acid; 6-Borono-2-phenylimidazo[1,2-a]pyridine; 2-Phenyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo[1,2-a]pyridine (Pinacol ester precursor); Imidazo[1,2-a]pyridine-6-boronic acid, 2-phenyl-; 1187822-25-8; 2-Phenylimidazo[1,2-a]pyridin-6-ylboronic acid
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Quality Control

Our 2-Phenylimidazo[1,2-A]Pyridine-6-Boronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, which is critical for sensitive cross-coupling reactions. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of pharmaceutical R&D and cGMP starting material standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) for long-term storage and when dispensing to prevent degradation.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 1.0%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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