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Imidazo[1,2-A]Pyridine, 2-Chloro-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- CAS NO 1187820-12-7
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CAS No.:1187820-12-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Imidazo[1,2-A]Pyridine, 2-Chloro-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is a high-value, functionalized heterocyclic boronic ester derivative. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily required by R&D and production teams in the pharmaceutical, agrochemical, and material science sectors for constructing complex molecular architectures.
Application
- Suzuki-Miyaura Cross-Coupling Reactions: As a key boronic ester reagent for forming carbon-carbon bonds in the synthesis of complex organic molecules.
- Pharmaceutical Intermediate: For the research and development of new active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery.
- Agrochemical Synthesis: As a building block for creating novel herbicides, fungicides, and insecticides with specific activity profiles.
- Material Science & OLED Development: In the synthesis of organic semiconductors, light-emitting materials, and other functional organic electronic components.
- Ligand Synthesis for Catalysis: For constructing novel nitrogen-containing ligands used in transition metal catalysis.
- Chemical Biology & Probe Development: As a handle for bioconjugation and the creation of molecular probes for biological target identification.
Basic Information
| Product Name | Imidazo[1,2-A]Pyridine, 2-Chloro-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- |
| CAS No. | 1187820-12-7 |
| Molecular Formula | C13H16BClN2O2 |
| Molecular Weight | 278.54 g/mol |
| Synonyms | 2-Chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo[1,2-a]pyridine; 2-Chloro-6-(tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo[1,2-a]pyridine; 2-Chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-imidazo[1,2-a]pyridine; 6-Boronic acid, 2-chloroimidazo[1,2-a]pyridine-, 1,3,2-dioxaborolane ester; 2-Chloro-6-(pinacolatoboryl)imidazo[1,2-a]pyridine; 2-Chloroimidazo[1,2-a]pyridine-6-boronic acid pinacol ester; Imidazo[1,2-a]pyridine-6-boronic acid, 2-chloro-, pinacol ester |
| EINECS | Contact for details |
Quality Control
Our production of Imidazo[1,2-A]Pyridine, 2-Chloro-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your critical synthesis workflows. Each lot is characterized by modern analytical techniques including HPLC, NMR (1H & 13C), and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (HPLC) | Conforms to reference standard |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% (Area Percent) |
| Water Content (KF) | ≤ 0.5% w/w |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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