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Imidazo[1,2-A]Pyridine, 2-Chloro-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- CAS NO 1187820-12-7


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CAS No.:1187820-12-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Imidazo[1,2-A]Pyridine, 2-Chloro-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is a high-value, functionalized heterocyclic boronic ester derivative. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily required by R&D and production teams in the pharmaceutical, agrochemical, and material science sectors for constructing complex molecular architectures.

Application

  • Suzuki-Miyaura Cross-Coupling Reactions: As a key boronic ester reagent for forming carbon-carbon bonds in the synthesis of complex organic molecules.
  • Pharmaceutical Intermediate: For the research and development of new active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery.
  • Agrochemical Synthesis: As a building block for creating novel herbicides, fungicides, and insecticides with specific activity profiles.
  • Material Science & OLED Development: In the synthesis of organic semiconductors, light-emitting materials, and other functional organic electronic components.
  • Ligand Synthesis for Catalysis: For constructing novel nitrogen-containing ligands used in transition metal catalysis.
  • Chemical Biology & Probe Development: As a handle for bioconjugation and the creation of molecular probes for biological target identification.

Basic Information

Product Name Imidazo[1,2-A]Pyridine, 2-Chloro-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-
CAS No. 1187820-12-7
Molecular Formula C13H16BClN2O2
Molecular Weight 278.54 g/mol
Synonyms 2-Chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo[1,2-a]pyridine; 2-Chloro-6-(tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo[1,2-a]pyridine; 2-Chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-imidazo[1,2-a]pyridine; 6-Boronic acid, 2-chloroimidazo[1,2-a]pyridine-, 1,3,2-dioxaborolane ester; 2-Chloro-6-(pinacolatoboryl)imidazo[1,2-a]pyridine; 2-Chloroimidazo[1,2-a]pyridine-6-boronic acid pinacol ester; Imidazo[1,2-a]pyridine-6-boronic acid, 2-chloro-, pinacol ester
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Quality Control

Our production of Imidazo[1,2-A]Pyridine, 2-Chloro-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your critical synthesis workflows. Each lot is characterized by modern analytical techniques including HPLC, NMR (1H & 13C), and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (HPLC) Conforms to reference standard
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0% (Area Percent)
Water Content (KF) ≤ 0.5% w/w
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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