Description

3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thiophene-2-Carboxylic Acid is a high-purity, versatile organoboron building block essential for modern synthetic chemistry. This compound serves as a critical intermediate in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with complex heterocyclic structures.
• Material Science: Precursor for creating conjugated polymers and organic electronic materials for applications in OLEDs and sensors.
• Chemical Synthesis: Versatile reagent for introducing the thiophene-carboxylic acid moiety into larger, more complex organic molecules.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in catalytic systems.
• Academic & R&D: Essential tool for methodological development and exploration of new synthetic pathways in organic chemistry laboratories.

Basic Information

Item	Details
Product Name	3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thiophene-2-Carboxylic Acid
CAS No.	1187591-40-7
Molecular Formula	C11H15BO4S
Molecular Weight	254.11 g/mol
Synonyms	2-Thiophenecarboxylic acid, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-2-carboxylic acid; 3-Pinacolatoborylthiophene-2-carboxylic Acid; 3-Boronothiophene-2-carboxylic Acid Pinacol Ester; Thiophene-3-boronic acid pinacol ester-2-carboxylic acid; 1187591-40-7; 3-(Pinacolatoboryl)thiophene-2-carboxylic Acid
EINECS	Contact for details

Quality Control

Our 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thiophene-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.