Description

2-Carboxyphenylboronic Acid, Pinacol Ester is a protected boronic acid derivative, a crucial intermediate in modern synthetic organic chemistry. Its core value lies in its enhanced stability compared to the free boronic acid, facilitating handling and storage while remaining a versatile building block for Suzuki-Miyaura cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for constructing complex biaryl and heterobiaryl structures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing biphenyl or phenyl-heteroaryl motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Material Science: Serves as a monomer or precursor in the development of organic electronic materials, such as polymers for OLEDs and organic photovoltaics.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and affinity ligands for studying biological processes and protein interactions.
• Ligand Synthesis: A precursor for creating sophisticated chiral and achiral ligands used in asymmetric catalysis and metal complexation.
• Academic & Contract Research: A valuable reagent for methodology development and complex molecule synthesis in research laboratories and CROs.

Basic Information

Product Name	2-Carboxyphenylboronic Acid, Pinacol Ester
CAS No.	1187591-17-8
Molecular Formula	C14H19BO4
Molecular Weight	262.11 g/mol
Synonyms	2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic Acid; Benzoic acid, 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 2-Carboxyphenylboronic Acid Pinacol Ester; 2-Boronobenzoic Acid Pinacol Ester; o-Carboxyphenylboronic Acid Pinacol Ester; 2-(Pinacolatoboryl)benzoic Acid; Pinacol 2-Carboxyphenylboronate
EINECS	Contact for details

Quality Control

Our 2-Carboxyphenylboronic Acid, Pinacol Ester is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.