Description

Methanone, Cyclobutyl-1-Pyrrolidinyl- is a high-value organic intermediate featuring a cyclobutyl ketone core substituted with a pyrrolidine moiety, offering a unique structural motif for advanced chemical synthesis. This compound is critical for research and development in pharmaceutical chemistry, where it serves as a versatile building block for creating novel molecular entities. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its constrained cyclobutyl ring and amine functionality.
• Agrochemical Synthesis: Intermediate in the development of new generation herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science Precursor: Potential monomer or cross-linking agent in the development of specialty polymers with tailored properties.
• Chemical Biology Probe: Used to create tool compounds for studying biological pathways and protein function.

Basic Information

Product Name	Methanone, Cyclobutyl-1-Pyrrolidinyl-
CAS No.	1187369-48-7
Molecular Formula	C9H15NO
Molecular Weight	153.22 g/mol
Synonyms	Cyclobutyl(pyrrolidin-1-yl)methanone; 1-(Cyclobutanecarbonyl)pyrrolidine; N-(Cyclobutanecarbonyl)pyrrolidine; Pyrrolidine, 1-cyclobutanecarbonyl-; Cyclobutanoylpyrrolidine; 1-Cyclobutanoyl-pyrrolidine; Cyclobutyl 1-pyrrolidinyl ketone
EINECS	Contact for details

Quality Control

Our Methanone, Cyclobutyl-1-Pyrrolidinyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.