Description

2-(2-(Trifluoromethyl)Phenyl)Piperidine Hydrochloride is a high-purity, synthetically valuable organic building block and pharmaceutical intermediate. Its core value lies in the trifluoromethylphenyl moiety, which is a critical structural feature for modulating the physicochemical and metabolic properties of bioactive molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on creating novel small-molecule therapeutics and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of novel drug candidates, especially in central nervous system (CNS) and metabolic disorder research.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Chemical Biology Probe Synthesis: Serves as a building block for creating molecular probes to study enzyme function and receptor interactions.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Academic & Institutional R&D: A valuable reagent for universities and research institutes conducting studies in medicinal chemistry and organic synthesis.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis projects and scale-up production under cGMP for clinical trial materials.

Basic Information

Product Name	2-(2-(Trifluoromethyl)Phenyl)Piperidine Hydrochloride
CAS No.	1187173-27-8
Molecular Formula	C12H14F3N·HCl
Molecular Weight	265.70 g/mol
Synonyms	2-[2-(Trifluoromethyl)phenyl]piperidine hydrochloride; 2-(2-Trifluoromethylphenyl)piperidine HCl; 1-(2-(Trifluoromethyl)phenyl)piperidin-2-one (precursor); α-(2-Trifluoromethylphenyl)piperidine hydrochloride; 2-(α,α,α-Trifluoro-o-tolyl)piperidine hydrochloride
EINECS	Contact for details

Quality Control

Our 2-(2-(Trifluoromethyl)Phenyl)Piperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.