Description

2-(2,3-Difluorobenzoyl)-4-Methylpyridine is a high-purity, advanced pharmaceutical intermediate characterized by its specific difluorobenzoyl-substituted pyridine structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular modification. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Serves as a precursor in the development of new-generation herbicides and fungicides, leveraging the biological activity of the difluorobenzoyl moiety.
• Material Science: Used in the research and development of advanced organic electronic materials and liquid crystals due to its specific aromatic and fluorinated structure.
• Chemical Synthesis: Acts as a versatile reagent for introducing the 2,3-difluorobenzoyl group into complex molecules in medicinal and synthetic chemistry.
• Contract Research & Development (CRO/CMO): Supplied to research organizations for custom synthesis projects and process optimization studies.

Basic Information

Product Name	2-(2,3-Difluorobenzoyl)-4-Methylpyridine
CAS No.	1187170-98-4
Molecular Formula	C13H9F2NO
Molecular Weight	233.21 g/mol
Synonyms	4-Methyl-2-(2,3-difluorobenzoyl)pyridine; 2-(2,3-Difluorobenzoyl)-4-picoline; 2,3-Difluoro-4'-methyl-2-pyridinylphenylmethanone; (2,3-Difluorophenyl)(4-methylpyridin-2-yl)methanone; 1187170-98-4; 2-(2,3-Difluorobenzoyl)-4-methylpyridine; 4-Methyl-2-(2,3-difluorobenzoyl)pyridine
EINECS	Contact for details

Quality Control

Our 2-(2,3-Difluorobenzoyl)-4-Methylpyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.