Description

2-(3,5-Difluorobenzoyl)-4-Methylpyridine is a high-purity, advanced pharmaceutical intermediate characterized by its distinct difluorobenzoyl and methylpyridine structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular modification. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic research.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, leveraging the fluorine atoms for enhanced biological activity and stability.
• Material Science: Serves as a precursor for the synthesis of specialized ligands and organic compounds used in catalysis and advanced polymer research.
• Academic & R&D: Employed in university and corporate laboratories for methodological studies in organic synthesis and fluorochemistry.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke molecules for client projects.

Basic Information

Product Name	2-(3,5-Difluorobenzoyl)-4-Methylpyridine
CAS No.	1187167-05-0
Molecular Formula	C13H9F2NO
Molecular Weight	233.21 g/mol
Synonyms	4-Methyl-2-(3,5-difluorobenzoyl)pyridine; 2-(3,5-Difluorobenzoyl)-4-picoline; 4-Picoline, 2-(3,5-difluorobenzoyl)-; 1187167-05-0; (3,5-Difluorophenyl)(4-methylpyridin-2-yl)methanone
EINECS	Contact for details

Quality Control

Our 2-(3,5-Difluorobenzoyl)-4-Methylpyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.