Description

6-Methoxy-2-(3-Trifluoromethylbenzoyl)Pyridine is a high-value, functionalized pyridine derivative characterized by its methoxy and trifluoromethylbenzoyl substituents. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Serves as a building block for developing new-generation herbicides, fungicides, and insecticides, leveraging the biological activity of the pyridine and trifluoromethyl motifs.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis, including those for cross-coupling reactions in fine chemical synthesis.
• Material Science: Acts as a monomer or functional additive in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: A valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis for high-throughput screening.

Basic Information

Product Name	6-Methoxy-2-(3-Trifluoromethylbenzoyl)Pyridine
CAS No.	1187167-03-8
Molecular Formula	C14H10F3NO2
Molecular Weight	281.23 g/mol
Synonyms	2-(3-(Trifluoromethyl)benzoyl)-6-methoxypyridine; 6-Methoxy-2-[3-(trifluoromethyl)benzoyl]pyridine; 3'-Trifluoromethyl-6-methoxy-2-benzoylpyridine; 2-Benzoyl-6-methoxy-3'-(trifluoromethyl)pyridine; [6-Methoxy-2-pyridinyl][3-(trifluoromethyl)phenyl]methanone
EINECS	Contact for details

Quality Control

Every batch of 6-Methoxy-2-(3-Trifluoromethylbenzoyl)Pyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Any individual impurity ≤0.5%; Total impurities ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.