Description

3-(3-Bromophenyl)-2',4'-Difluoropropiophenone is a high-purity, specialized organic intermediate featuring a bromophenyl and difluoropropiophenone scaffold. This compound matters for its role as a critical building block in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders or possessing specific receptor binding profiles.
• Agrochemical Research: Used in the development of new generation herbicides, fungicides, or insecticides, leveraging the fluorine and bromine atoms for enhanced biological activity and environmental stability.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, or organic electronic materials.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and other catalytic transformations to construct complex biaryl and conjugated systems.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploratory synthesis projects.

Basic Information

Product Name	3-(3-Bromophenyl)-2',4'-Difluoropropiophenone
CAS No.	1187165-93-0
Molecular Formula	C15H11BrF2O
Molecular Weight	325.15 g/mol
Synonyms	1-(3-Bromophenyl)-3-(2,4-difluorophenyl)propan-1-one; 3-(3-Bromophenyl)-1-(2,4-difluorophenyl)propan-1-one; 2',4'-Difluoro-3-(3-bromophenyl)propiophenone; 3-Bromo-3'-phenyl-2,4'-difluoropropiophenone; Propiophenone, 3-(3-bromophenyl)-2',4'-difluoro-; (3-Bromophenyl)(2,4-difluorophenyl)propanone
EINECS	Contact for details

Quality Control

Our 3-(3-Bromophenyl)-2',4'-Difluoropropiophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring traceability and consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.