Description

2-(2,3-Difluorobenzoyl)-6-Methylpyridine is a high-purity, specialized organic building block featuring a difluorobenzoyl moiety linked to a methylpyridine core. This compound is valued for its precise molecular architecture, which is critical for modulating the physicochemical and biological properties of advanced materials and active pharmaceutical ingredients. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for use in medicinal chemistry, process development, and as a key intermediate in the synthesis of novel compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and pesticides where the difluorobenzoyl group enhances bioactivity and environmental stability.
• Material Science Research: Serves as a building block for developing specialty polymers, liquid crystals, or organic electronic materials.
• Chemical Biology & Probe Development: Utilized in the design of molecular probes and inhibitors for biochemical and pharmacological studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.
• Academic & Industrial R&D: Employed in exploratory chemistry for discovering new reactions and catalytic processes involving fluorinated aromatics.

Basic Information

Product Name	2-(2,3-Difluorobenzoyl)-6-Methylpyridine
CAS No.	1187164-58-4
Molecular Formula	C13H9F2NO
Molecular Weight	233.21 g/mol
Synonyms	6-Methyl-2-(2,3-difluorobenzoyl)pyridine; 2-(2,3-Difluorobenzoyl)-6-picoline; (2,3-Difluorophenyl)(6-methylpyridin-2-yl)methanone; 2,3-Difluoro-6'-(methyl)-2-pyridinylphenylmethanone; 2-Pyridinecarboxaldehyde, 6-methyl-, (2,3-difluorophenyl)hydrazone (related derivative); 2,3-Difluoro-α-oxo-6-picolinebenzenemethanol (tautomeric form)
EINECS	Contact for details

Quality Control

Every batch of 2-(2,3-Difluorobenzoyl)-6-Methylpyridine is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.