Description

2-Homomorpholinecarboxylic Acid Hydrochloride is a high-purity organic building block and pharmaceutical intermediate of significant commercial interest. Its value lies in its role as a key synthon for constructing complex molecules, particularly in medicinal chemistry and advanced material science. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for synthesis and process development.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the morpholine scaffold for bioactivity.
• Chemical Research & Development: A versatile synthon for academic and industrial R&D in organic chemistry, enabling the exploration of new chemical spaces and reaction pathways.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Peptidomimetics and Bio-conjugates: Acts as a constrained amino acid analog for creating peptide-like structures with enhanced metabolic stability and bioavailability.
• Material Science Precursor: Utilized in the development of advanced polymers and functional materials with specific chemical or physical properties.

Basic Information

Product Name	2-Homomorpholinecarboxylic Acid Hydrochloride
CAS No.	1186663-62-6
Molecular Formula	C6H11NO3 • HCl
Molecular Weight	197.62 g/mol
Synonyms	2-(Aminomethyl)morpholine-4-carboxylic acid hydrochloride; 4-Carboxy-2-aminomethylmorpholine hydrochloride; 2-(Aminomethyl)-4-morpholinecarboxylic acid hydrochloride; Homomorpholine-2-carboxylic acid HCl; 2-Carboxymethylaminomorpholine hydrochloride; Morpholine-2-acetic acid derivative hydrochloride; 2-(Morpholin-2-yl)acetic acid hydrochloride (tautomeric form).
EINECS	Contact for details

Quality Control

Our 2-Homomorpholinecarboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets exacting standards for research and commercial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.