Description

3'-Bromo-4'-(1H-Pyrazol-1-Yl)Acetophenone is a high-purity organic building block characterized by its bromo-substituted acetophenone core linked to a pyrazole moiety. This compound is valued for its role as a versatile synthetic intermediate in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists working on novel active ingredients, particularly in medicinal chemistry for hit-to-lead optimization.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of small molecule drug candidates, particularly those targeting kinase inhibition.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides by serving as a core scaffold for structure-activity relationship (SAR) studies.
• Material Science: Potential building block for creating specialized organic ligands and functional polymers.
• Chemical Biology: Useful as a probe or linker in the development of biochemical tools and assay components.
• Academic & Contract Research: Employed in university and CRO laboratories for method development and novel synthetic route exploration.

Basic Information

Product Name	3'-Bromo-4'-(1H-Pyrazol-1-Yl)Acetophenone
CAS No.	1186663-58-0
Molecular Formula	C11H9BrN2O
Molecular Weight	265.11 g/mol
Synonyms	1-[3-Bromo-4-(1H-pyrazol-1-yl)phenyl]ethanone; 3'-Bromo-4'-(pyrazol-1-yl)acetophenone; 1-(3-Bromo-4-(1H-pyrazol-1-yl)phenyl)ethan-1-one; 3-Bromo-4-(1-pyrazolyl)acetophenone; 3-Bromo-4-(pyrazol-1-yl)acetophenone; Ethanone, 1-[3-bromo-4-(1H-pyrazol-1-yl)phenyl]-; 1186663-58-0
EINECS	Contact for details

Quality Control

Our 3'-Bromo-4'-(1H-Pyrazol-1-Yl)Acetophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.