Description

2-Chloro-4-(1H-Pyrazol-1-Yl)Benzaldehyde is a high-value aromatic aldehyde building block featuring a chlorophenyl core linked to a pyrazole heterocycle. This unique bifunctional structure makes it a critical intermediate for the synthesis of advanced molecules in life sciences research and development. It is primarily sought after by pharmaceutical and agrochemical R&D teams for constructing novel active ingredients. The compound's reactivity profile allows for selective modifications at both the aldehyde and halogen sites, enabling efficient scaffold diversification.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel small-molecule drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Active Ingredient Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic core.
• Material Science & Organic Electronics: Serves as a precursor for functionalized ligands and organic semiconductors due to its conjugated system.
• Chemical Biology & Probe Development: Employed in creating fluorescent probes or affinity tags for studying biological targets and pathways.
• Cross-Coupling Reactions: The chloro substituent makes it a suitable substrate for palladium-catalyzed coupling reactions (e.g., Suzuki, Buchwald-Hartwig).
• Heterocyclic Chemistry: Core component for constructing more complex polyheterocyclic systems via condensation and cyclization reactions.

Basic Information

Product Name	2-Chloro-4-(1H-Pyrazol-1-Yl)Benzaldehyde
CAS No.	1186663-54-6
Molecular Formula	C10H7ClN2O
Molecular Weight	206.63 g/mol
Synonyms	2-Chloro-4-(1H-pyrazol-1-yl)benzaldehyde; 4-(1H-Pyrazol-1-yl)-2-chlorobenzaldehyde; 2-Chloro-4-(pyrazol-1-yl)benzaldehyde; Benzaldehyde, 2-chloro-4-(1H-pyrazol-1-yl)-; 1-(4-Formyl-3-chlorophenyl)-1H-pyrazole; 2-Chloro-4-(1H-pyrazol-1-yl)benzenecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(1H-Pyrazol-1-Yl)Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide Certificates of Analysis (COA) with detailed specifications for traceability and quality assurance, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.