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7-Methoxy-1H-Indazole-4-Boronic Acid CAS NO 1186422-15-0


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CAS No.:1186422-15-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

7-Methoxy-1H-Indazole-4-Boronic Acid is a high-purity boronic acid derivative and a key synthetic intermediate in modern organic chemistry. Its primary value lies in its role as a versatile building block for the Suzuki-Miyaura cross-coupling reaction, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional organic materials.

Application

  • Pharmaceutical Intermediate: A critical precursor in the synthesis of drug candidates, especially those containing the indazole pharmacophore for oncology, CNS, and anti-inflammatory applications.
  • Agrochemical Research: Used to create novel herbicides, fungicides, and insecticides by constructing complex molecular architectures.
  • Material Science: Serves as a monomer or building block for creating advanced organic electronic materials, such as OLEDs and organic semiconductors.
  • Chemical Synthesis: A versatile reagent in Suzuki-Miyaura cross-coupling reactions for C-C bond formation in academic and industrial R&D laboratories.
  • Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
  • Library Synthesis: Used in combinatorial and parallel synthesis for high-throughput screening of compound libraries in drug discovery.

Basic Information

Product Name 7-Methoxy-1H-Indazole-4-Boronic Acid
CAS No. 1186422-15-0
Molecular Formula C8H9BN2O3
Molecular Weight 192.00 g/mol
Synonyms 7-Methoxy-1H-indazole-4-boronic acid; (7-Methoxy-1H-indazol-4-yl)boronic acid; 4-Borono-7-methoxy-1H-indazole; 7-Methoxy-4-indazoleboronic acid; 7-Methoxyindazole-4-boronic Acid; B-(7-Methoxy-1H-indazol-4-yl)boronic acid; 1186422-15-0; 7-Methoxy-1H-indazol-4-ylboronic acid
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Quality Control

Our 7-Methoxy-1H-Indazole-4-Boronic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep the container tightly sealed in a desiccator for long-term storage.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms
Identification (NMR) Conforms
Purity (HPLC) ≥97.0%
Water Content (KF) ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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