Description

2-[3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-1,3,4-Oxadiazole is a high-value, multi-functional organic building block that combines an oxadiazole heterocycle with a protected boronic ester moiety. This compound matters for its critical role as a key intermediate in modern synthetic chemistry, enabling the construction of complex molecules through versatile cross-coupling reactions. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries for developing new active ingredients and advanced functional materials. The product is supplied with a guaranteed CAS No. 1186334-84-8 to ensure precise identification and supply chain integrity.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates, particularly in constructing complex heterocyclic cores for oncology, CNS, and anti-infective therapies.
• Suzuki-Miyaura Cross-Coupling Reactions: The protected boronic ester group acts as a stable handle for palladium-catalyzed coupling with aryl/heteroaryl halides, enabling efficient carbon-carbon bond formation.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the oxadiazole scaffold.
• Organic Light-Emitting Diodes (OLEDs): Functions as an electron-transporting or host material precursor in the manufacture of advanced display and lighting technologies.
• Ligand Synthesis for Catalysis: Employed in the preparation of specialized ligands for transition metal catalysts used in asymmetric synthesis.
• Polymer & Material Science: Incorporated into polymers and advanced materials to impart specific electronic or thermal properties.
• Chemical Biology Probes: Utilized in the development of molecular probes and tags for studying biological processes and target engagement.

Basic Information

Product Name	2-[3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-1,3,4-Oxadiazole
CAS No.	1186334-84-8
Molecular Formula	C14H18BN2O3
Molecular Weight	273.12 g/mol
Synonyms	3-(1,3,4-Oxadiazol-2-yl)phenylboronic acid pinacol ester; 2-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1,3,4-oxadiazole; 1,3,4-Oxadiazole, 2-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-; 3-(2-Oxadiazolyl)phenylboronic acid pinacol ester; 2-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-1,3,4-oxadiazole; B-(3-(1,3,4-Oxadiazol-2-yl)phenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-[3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-1,3,4-Oxadiazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance in cGMP environments for pharmaceutical development and other high-purity applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opened for use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.