Description

4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-1,3-Dihydro-Benzoimidazol-2-One is a high-value, organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling efficient cross-coupling reactions, specifically Suzuki-Miyaura couplings, which are fundamental for constructing complex molecular architectures. This compound is critically needed by pharmaceutical R&D teams, agrochemical innovators, and advanced material scientists for the development of new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides with improved efficacy.
• Material Science: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and activity-based protein profiling (ABPP) reagents.
• Ligand & Catalyst Development: Utilized to synthesize novel bidentate ligands and complex catalysts for asymmetric synthesis.
• Academic & Contract Research: A vital reagent for methodology development and complex molecule construction in academic and CRO laboratories.

Basic Information

Product Name	4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-1,3-Dihydro-Benzoimidazol-2-One
CAS No.	1186334-82-6
Molecular Formula	C13H17BN2O3
Molecular Weight	260.10 g/mol
Synonyms	2-Oxo-1,3-dihydrobenzimidazole-4-boronic acid pinacol ester; 1,3-Dihydro-2H-benzimidazol-2-one, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d]imidazol-2(3H)-one; 4-(Pinacolatoboryl)-1,3-dihydro-2H-benzimidazol-2-one; Benzimidazolone-4-boronic acid pinacol ester; CAS 1186334-82-6
EINECS	Contact for details

Quality Control

Our 4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-1,3-Dihydro-Benzoimidazol-2-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent performance for critical coupling reactions. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its moisture-sensitive and easily oxidized nature. Allow the sealed container to reach room temperature before opening to prevent condensation and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.