Description

7-Fluoro-1H-Indazole-4-Boronic Acid Pinacol Ester is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its value lies in enabling efficient, selective cross-coupling reactions, such as the Suzuki-Miyaura reaction, which are fundamental to constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional organic materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of fluorinated indazole-based drug candidates, leveraging the Suzuki-Miyaura cross-coupling reaction.
• Agrochemical Research: Used to create novel fluorinated heterocyclic compounds with potential herbicidal, fungicidal, or insecticidal activity.
• Material Science: Serves as a precursor for constructing organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters or charge-transport molecules.
• Chemical Biology & Probe Development: Employed in the synthesis of fluorinated molecular probes and tags for imaging and diagnostic applications.
• Academic & Contract Research: A valuable reagent for methodology development and exploring new synthetic routes in academic and industrial R&D laboratories.

Basic Information

Item	Details
Product Name	7-Fluoro-1H-Indazole-4-Boronic Acid Pinacol Ester
CAS No.	1186334-64-4
Molecular Formula	C₁₃H₁₆BFN₂O₂
Molecular Weight	262.09 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-7-fluoro-1H-indazole; 7-Fluoro-1H-indazole-4-boronic acid pinacol ester; 7-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole; 7-Fluoro-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole; 4-Borono-7-fluoro-1H-indazole pinacol ester; 7-Fluoroindazole-4-boronic acid pinacol ester; PINACOL 7-FLUORO-1H-INDAZOLE-4-BORONATE
EINECS	Contact for details

Quality Control

Our 7-Fluoro-1H-Indazole-4-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR (¹H, ¹³C, ¹⁹F), and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.