Description

7-Chloro-1H-Indazole-4-Boronic Acid Pinacol Ester is a high-purity, synthetically valuable boronic ester derivative, serving as a critical building block in modern organic synthesis. Its core value lies in enabling efficient cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel indazole-based drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Employed in the synthesis of organic electronic materials, such as ligands for OLEDs and other functional polymers.
• Chemical Biology: Serves as a versatile probe or building block in the synthesis of biologically active molecules for target identification and validation.
• Catalyst & Ligand Development: Utilized in the preparation of novel boron-containing ligands for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	7-Chloro-1H-Indazole-4-Boronic Acid Pinacol Ester
CAS No.	1186334-62-2
Molecular Formula	C₁₃H₁₆BClN₂O₂
Molecular Weight	278.54 g/mol
Synonyms	7-Chloro-1H-indazol-4-ylboronic acid pinacol ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-7-chloro-1H-indazole; 7-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole; 7-Chloro-1H-indazole-4-boronic acid, pinacol ester; B-(7-Chloro-1H-indazol-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 1186334-62-2; 7-Chloroindazole-4-boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 7-Chloro-1H-Indazole-4-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and structural integrity. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to consistent quality and traceability supports your research and development needs with reliable, specification-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.