Description

(4E)-6-[1,3-Dihydro-6-Methoxy-7-Methyl-3-Oxo-4-[(2,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranosyl)Oxy]-5-Isobenzofuranyl]-4-Methyl-4-Hexenoic Acid Methyl Ester is a high-purity, complex organic intermediate featuring a glucopyranosyl-substituted isobenzofuran core. This compound is of significant value for its role as a key synthetic precursor in advanced pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in oncology and metabolic disease research.
• Glycoconjugate Synthesis: Serves as a protected glycosyl donor or acceptor for constructing sophisticated glycoconjugates and carbohydrate-based drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new chemical entities.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant scale for clinical trial material production.
• Biochemical Probe Development: Utilized in the creation of labeled or modified compounds for studying biological pathways and target engagement.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the life sciences industry.

Basic Information

Product Name	(4E)-6-[1,3-Dihydro-6-Methoxy-7-Methyl-3-Oxo-4-[(2,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranosyl)Oxy]-5-Isobenzofuranyl]-4-Methyl-4-Hexenoic Acid Methyl Ester
CAS No.	1186295-42-0
Molecular Formula	C32H40O14
Molecular Weight	648.66 g/mol
Synonyms	Methyl (4E)-6-[4-[(2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl)oxy]-1,3-dihydro-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl]-4-methyl-4-hexenoate; 4-[(2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl)oxy]isobenzofuran-1-one derivative; Peracetylated glucosyl isobenzofuranyl hexenoate methyl ester; CAS 1186295-42-0; Glucopyranosyl-substituted Isobenzofuran Ester; Acetyl-protected Glycosyl Intermediate.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment. We support development under GMP-like conditions where required for pre-clinical and clinical stage materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light) and should be handled with care in strong acid/organic solvent environments. For long-term storage, consider inert atmosphere conditions to preserve stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.