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4-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thiazol-2-Yl)Morpholine CAS NO 1186115-52-5


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CAS No.:1186115-52-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thiazol-2-Yl)Morpholine is a high-value, organoboron building block critical for modern synthetic chemistry, particularly in cross-coupling reactions. Its core value lies in enabling the efficient and precise construction of complex molecular architectures, which is essential for developing new active compounds. This advanced intermediate is primarily needed by research and development teams in the pharmaceutical, agrochemical, and material science industries for drug discovery and fine chemical synthesis.

Application

  • Pharmaceutical Intermediate: Key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
  • Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides with improved efficacy.
  • Material Science: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and organic semiconductors.
  • Chemical Biology: Employed in the synthesis of probes and ligands for studying biological targets and pathways.
  • Academic & Industrial R&D: Essential reagent for methodological development and library synthesis in medicinal and combinatorial chemistry.
  • Fine Chemical Synthesis: Facilitates the production of complex, high-value specialty chemicals and custom synthesis projects.

Basic Information

Product Name 4-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thiazol-2-Yl)Morpholine
CAS No. 1186115-52-5
Molecular Formula C13H21BN2O3S
Molecular Weight 296.19 g/mol
Synonyms 4-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazol-2-yl]morpholine; 2-Morpholino-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-morpholinothiazole; 1186115-52-5; 4-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiazol-2-yl)morpholine; Boronic acid, B-[2-(4-morpholinyl)-4-thiazolyl]-, 4,4,5,5-tetramethyl-1,3,2-dioxaborolane ester
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Quality Control

Our 4-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thiazol-2-Yl)Morpholine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and LC-MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation. Keep away from incompatible materials.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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