Description

6-(1H-Pyrazol-1-Yl)Pyridine-2-Boronic Acid Pinacol Ester is a high-value boronic ester derivative, a crucial building block in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to develop new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel active pharmaceutical ingredients (APIs), especially in kinase inhibitor and other small-molecule drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific heterocyclic architectures.
• Material Science: Serves as a monomer or precursor for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Ligand Synthesis: Acts as a precursor for constructing sophisticated polydentate ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes and target engagement.
• Cross-Coupling Reactions: Specifically designed for palladium-catalyzed Suzuki-Miyaura cross-coupling to form carbon-carbon bonds under mild conditions.

Basic Information

Product Name	6-(1H-Pyrazol-1-Yl)Pyridine-2-Boronic Acid Pinacol Ester
CAS No.	1186115-51-4
Molecular Formula	C14H18BN3O2
Molecular Weight	271.13 g/mol
Synonyms	6-(1H-Pyrazol-1-yl)pyridine-2-boronic acid pinacol ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(1H-pyrazol-1-yl)pyridine; 6-(1H-Pyrazol-1-yl)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 6-Pyrazol-1-ylpyridine-2-boronic acid pinacol ester; 2-(1H-Pyrazol-1-yl)-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; Boronic acid, B-[6-(1H-pyrazol-1-yl)-2-pyridinyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. Each batch is characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry to confirm identity and purity. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We adhere to a quality management system to ensure traceability and consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.