Description

1-Ethyl-3-(4-(5-Phenyl-1,3,4-Oxadiazol-2-Yl)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Urea is a sophisticated organic compound that serves as a critical building block in advanced chemical synthesis. Its molecular architecture, featuring both a urea linkage and a protected boronic acid pinacol ester, makes it a versatile intermediate for constructing complex molecules with high precision. This compound is primarily utilized by research institutions and pharmaceutical developers engaged in medicinal chemistry, particularly for the synthesis of targeted therapeutics and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those targeting specific biological pathways.
• Medicinal Chemistry Research: Used in the design and development of new chemical entities for high-throughput screening and structure-activity relationship (SAR) studies.
• Suzuki-Miyaura Cross-Coupling Reactions: The pinacol boronate ester group enables efficient palladium-catalyzed cross-coupling to form carbon-carbon bonds, a fundamental reaction in constructing complex organic frameworks.
• Chemical Biology Probes: Serves as a precursor for creating labeled molecules and probes used to study biological processes and protein interactions.
• Material Science Research: Potential intermediate in the development of organic electronic materials and advanced polymers with specific functional properties.
• Agrochemical Synthesis: Used in the research phase for developing new, more effective crop protection agents.

Basic Information

Product Name	1-Ethyl-3-(4-(5-Phenyl-1,3,4-Oxadiazol-2-Yl)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Urea
CAS No.	1186113-72-3
Molecular Formula	C24H27BN6O4
Molecular Weight	474.33 g/mol
Synonyms	1-Ethyl-3-[4-(5-phenyl-1,3,4-oxadiazol-2-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]urea; Urea, N-ethyl-N'-[4-(5-phenyl-1,3,4-oxadiazol-2-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]-; 1186113-72-3; 2-Pyridinylurea derivative with boronate ester; Oxadiazole-pyridine-boronate urea derivative.
EINECS	Contact for details

Quality Control

Our production of 1-Ethyl-3-(4-(5-Phenyl-1,3,4-Oxadiazol-2-Yl)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Urea adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment and NMR for structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key specifications such as assay, identity, and impurity profiles to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and performance. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.