Description

2-Bromo-1-(6-Methoxypyridin-3-yl)ethanone is a versatile and high-value brominated ketone building block, essential for advanced organic synthesis. Its core value lies in its reactive bromoacetyl group attached to a methoxypyridine scaffold, making it a critical intermediate for constructing complex molecules with precision. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging the pyridine moiety for bioactivity.
• Chemical Research & Development: Serves as a versatile electrophile in cross-coupling reactions, nucleophilic substitutions, and heterocyclic chemistry for creating new chemical entities.
• Material Science Precursor: Potential intermediate in the synthesis of organic ligands for catalysts or functional polymers.
• Custom Synthesis & Contract Manufacturing: A critical starting material for CROs and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	2-Bromo-1-(6-Methoxypyridin-3-yl)ethanone
CAS No.	1186113-51-8
Molecular Formula	C8H8BrNO2
Molecular Weight	230.06 g/mol
Synonyms	2-Bromo-1-(6-methoxy-3-pyridinyl)ethanone; 2-Bromo-1-(6-methoxypyridin-3-yl)ethan-1-one; 3-Acetyl-6-methoxypyridine 2-bromo derivative; 6-Methoxy-3-pyridyl bromomethyl ketone; 2-Bromo-1-(6-methoxypyridin-3-yl)ethanone; α-Bromo-6-methoxynicotinoyl methyl ketone; 1186113-51-8
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-1-(6-Methoxypyridin-3-yl)ethanone is produced under strict quality management protocols. We guarantee high purity and consistency, with comprehensive testing including HPLC for assay and related substances. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to ensure it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Related Substances (HPLC)	Total impurities ≤3.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.