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6-(3-Ethylureido)-4-(4-Phenylthiazol-2-Yl)Pyridin-3-Ylboronic Acid CAS NO 1186112-31-1


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CAS No.:1186112-31-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

6-(3-Ethylureido)-4-(4-Phenylthiazol-2-Yl)Pyridin-3-Ylboronic Acid is a sophisticated boronic acid derivative and a key synthetic intermediate in modern pharmaceutical and agrochemical research. Its molecular structure, featuring a phenylthiazole-pyridine core, makes it a valuable building block for constructing complex molecules via Suzuki-Miyaura cross-coupling reactions. This compound is primarily sought after by research scientists and process chemists in the pharmaceutical industry for the development of new active pharmaceutical ingredients (APIs) and by agrochemical researchers for novel crop protection agents.

Application

  • Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in oncology, antiviral, and anti-inflammatory research pipelines.
  • Agrochemical Synthesis: Used as a building block for creating advanced active ingredients in herbicides, fungicides, and insecticides.
  • Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, due to its conjugated system.
  • Chemical Biology Probes: Serves as a versatile handle for bioconjugation and the development of molecular probes for diagnostic applications.
  • Catalyst Ligand Precursor: Can be utilized to synthesize novel ligands for transition metal catalysts used in asymmetric synthesis.
  • Academic & Contract Research: Essential for methodological development and discovery chemistry in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name 6-(3-Ethylureido)-4-(4-Phenylthiazol-2-Yl)Pyridin-3-Ylboronic Acid
CAS No. 1186112-31-1
Molecular Formula C₁₇H₁₇BN₄O₂S
Molecular Weight 352.22 g/mol
Synonyms 4-(4-Phenyl-1,3-thiazol-2-yl)-6-[(ethylcarbamoyl)amino]pyridin-3-ylboronic acid; 6-[(Ethylcarbamoyl)amino]-4-(4-phenyl-1,3-thiazol-2-yl)pyridin-3-ylboronic acid; 6-(3-Ethylureido)-4-(4-phenylthiazol-2-yl)pyridine-3-boronic acid; Boronic acid, B-[6-[(ethylamino)carbonyl]amino]-4-(4-phenyl-2-thiazolyl)-3-pyridinyl]-; 1186112-31-1; AKOS025310947; BCP34020
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Quality Control

Every batch of 6-(3-Ethylureido)-4-(4-Phenylthiazol-2-Yl)Pyridin-3-Ylboronic Acid is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. Certificates of Analysis (COA) detailing purity (typically by HPLC), identity (by NMR, IR), and impurity profiles are available for every shipment. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and moisture-sensitive nature. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95%
Water Content (KF) ≤ 1.0%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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