Description

5-Dimethylaminopyrazine-2-Boronic Acid Pinacol Ester is a high-value, organoboron building block essential for modern synthetic chemistry. This compound matters as a key intermediate in cross-coupling reactions, enabling the efficient construction of complex heterocyclic scaffolds. It is primarily needed by pharmaceutical, agrochemical, and advanced materials researchers for the development of new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly those containing functionalized pyrazine cores.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require specific heterocyclic architectures.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic semiconductors.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and tags for studying biological processes due to its boronic ester functionality.
• Catalyst Ligand Preparation: Utilized to synthesize novel ligand systems for transition metal catalysts used in fine chemical production.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	5-Dimethylaminopyrazine-2-Boronic Acid Pinacol Ester
CAS No.	1186041-96-2
Molecular Formula	C13H20BN3O2
Molecular Weight	261.13 g/mol
Synonyms	5-(Dimethylamino)pyrazine-2-boronic acid pinacol ester; 2-(5-Dimethylaminopyrazin-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (5-(Dimethylamino)pyrazin-2-yl)boronic acid pinacol ester; 5-Dimethylamino-2-pyrazineboronic acid pinacol ester; Pinacol [5-(dimethylamino)pyrazin-2-yl]boronate; CAS 1186041-96-2; DMAP-BPin
EINECS	Contact for details

Quality Control

Our 5-Dimethylaminopyrazine-2-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for sensitive cross-coupling applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.