Description

B-(4-Formyl-2-Thienyl)Boronic Acid is a high-value, multifunctional organoboron building block characterized by its reactive formyl and boronic acid functional groups. This compound is essential for facilitating complex carbon-carbon and carbon-heteroatom bond formations, particularly in metal-catalyzed cross-coupling reactions. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel thiophene-containing molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl and heterobiaryl scaffolds found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used to create novel thiophene-based herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Serves as a monomer or building block for developing conjugated polymers, organic semiconductors, and non-linear optical (NLO) materials.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for transition metal catalysis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and inhibitors for biological target identification.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	B-(4-Formyl-2-Thienyl)Boronic Acid
CAS No.	1186026-19-6
Molecular Formula	C5H5BO3S
Molecular Weight	155.97 g/mol
Synonyms	(4-Formylthiophen-2-yl)boronic acid; 2-Formyl-4-thienylboronic acid; 4-Formyl-2-thienylboronic acid; 2-Borono-4-formylthiophene; 5-Formyl-2-thienylboronic acid; Thiophene-2-boronic acid, 4-formyl-; (4-Formyl-2-thienyl)boronic acid
EINECS	Contact for details

Quality Control

Every batch of B-(4-Formyl-2-Thienyl)Boronic Acid is manufactured and tested under strict quality management protocols. We provide comprehensive analytical data including HPLC purity, NMR (1H, 13C, 11B) confirmation, and elemental analysis to ensure identity, potency, and consistency. Certificates of Analysis (COA) are available for each lot and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.