Description

2-Cyclopropylmethoxy-5-Methylphenylboronic Acid Pinacol Ester is a high-purity, synthetically valuable boronic ester derivative used as a key building block in modern organic synthesis. Its primary value lies in enabling efficient cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-quality intermediates for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A crucial precursor in Suzuki-Miyaura cross-couplings for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides.
• Material Science: Serves as a monomer or building block for creating organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D focused on C-C bond formation and medicinal chemistry.
• Ligand Synthesis: Can be utilized in the preparation of specialized ligands for catalysis.
• Library Synthesis: Enables the rapid generation of diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	2-Cyclopropylmethoxy-5-Methylphenylboronic Acid Pinacol Ester
CAS No.	1185836-99-0
Molecular Formula	C₁₇H₂₅BO₃
Molecular Weight	288.19 g/mol
Synonyms	[2-(Cyclopropylmethoxy)-5-methylphenyl]boronic acid pinacol ester; 5-Methyl-2-(cyclopropylmethoxy)phenylboronic acid pinacol ester; 2-(Cyclopropylmethoxy)-5-methylbenzeneboronic acid pinacol ester; Boronic acid, B-[2-(cyclopropylmethoxy)-5-methylphenyl]-, 1,1-dimethylethyl ester; 2-Cyclopropylmethoxy-5-methylbenzeneboronic acid pinacol ester; Pinacol [2-(cyclopropylmethoxy)-5-methylphenyl]boronate
EINECS	Contact for details

Quality Control

Our 2-Cyclopropylmethoxy-5-Methylphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC, to ensure high purity and batch-to-batch consistency suitable for sensitive coupling reactions. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.