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2-Cyclopropylmethoxyphenylboronic Acid Pinacol Ester CAS NO 1185836-98-9


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CAS No.:1185836-98-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Cyclopropylmethoxyphenylboronic Acid Pinacol Ester is a high-purity, synthetically valuable organoboron building block. This compound is essential for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for constructing complex molecular architectures.

Application

  • Pharmaceutical Intermediate: A key reagent in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biaryl or heterobiaryl motifs.
  • Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
  • Material Science Research: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
  • Chemical Biology & Probe Development: Employed in the construction of molecular probes and tools for studying biological pathways and target engagement.
  • Catalyst Ligand Synthesis: Acts as a starting material for the preparation of sophisticated ligand systems used in homogeneous catalysis.
  • Custom Synthesis & Contract Manufacturing: A critical component for CROs and CDMOs offering bespoke chemical synthesis services to global clients.

Basic Information

Product Name 2-Cyclopropylmethoxyphenylboronic Acid Pinacol Ester
CAS No. 1185836-98-9
Molecular Formula C₁₆H₂₃BO₃
Molecular Weight 274.17 g/mol
Synonyms 2-(Cyclopropylmethoxy)phenylboronic Acid Pinacol Ester; [2-(Cyclopropylmethoxy)phenyl]boronic Acid Pinacol Ester; 2-Cyclopropylmethoxybenzeneboronic Acid Pinacol Ester; (2-(Cyclopropylmethoxy)phenyl)boronic Acid Pinacol Ester; 2-(Cyclopropylmethoxy)phenyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol 2-(Cyclopropylmethoxy)phenylboronate
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Quality Control

Every batch of 2-Cyclopropylmethoxyphenylboronic Acid Pinacol Ester is manufactured under strict quality management protocols. We employ advanced analytical techniques including NMR, HPLC, and GC to ensure identity, purity, and consistency meet the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed under an inert atmosphere to maintain stability and prevent moisture ingress.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Assay ≥ 95.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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