Description

1-(3-Bromo-4-Cyclopropylmethoxyphenyl)-Ethanone is a high-purity, advanced pharmaceutical intermediate characterized by its distinct brominated aromatic ketone structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals, offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific functional groups into molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic programs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, leveraging the cyclopropyl and bromo substituents for bioactivity.
• Material Science Research: Serves as a precursor for the development of organic electronic materials, liquid crystals, and advanced polymers.
• Chemical Biology Probes: Employed in the creation of molecular probes and tags for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Item	Details
Product Name	1-(3-Bromo-4-Cyclopropylmethoxyphenyl)-Ethanone
CAS No.	1185836-84-3
Molecular Formula	C₁₂H₁₃BrO₂
Molecular Weight	269.14 g/mol
Synonyms	3'-Bromo-4'-cyclopropylmethoxyacetophenone; 1-(3-Bromo-4-(cyclopropylmethoxy)phenyl)ethanone; 3-Bromo-4-(cyclopropylmethoxy)acetophenone; 1-Acetyl-3-bromo-4-cyclopropylmethoxybenzene; 1-(3-Bromo-4-(cyclopropoxymethyl)phenyl)ethanone; Ethanone, 1-[3-bromo-4-(cyclopropylmethoxy)phenyl]-; 3-Bromo-4-cyclopropylmethoxyacetophenone
EINECS	Contact for details

Quality Control

Every batch of 1-(3-Bromo-4-Cyclopropylmethoxyphenyl)-Ethanone is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles where applicable, supporting our clients' regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.