Description

(1-Benzyl-3-Fluoro-3-Piperidyl)Methanamine CAS NO 1185749-68-1 is a specialized fluorinated piperidine derivative, a high-value building block in modern synthetic chemistry. Its molecular structure, featuring both a benzyl group and a fluorine atom on the piperidine ring, makes it a critical intermediate for constructing complex pharmacologically active molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to introduce fluorinated motifs to enhance the metabolic stability, bioavailability, and binding affinity of new chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology drug discovery programs.
• Agrochemical Research: Used in the synthesis of advanced herbicides, fungicides, and pesticides where the fluorine atom can improve lipophilicity and target activity.
• Chemical Biology Probe Development: Serves as a versatile scaffold for creating molecular probes to study enzyme function and receptor interactions.
• Ligand Synthesis for Catalysis: Employed in the preparation of sophisticated chiral ligands and catalysts for asymmetric synthesis.
• Material Science Precursor: Potential use in synthesizing specialty polymers and advanced materials with unique properties.

Basic Information

Product Name	(1-Benzyl-3-Fluoro-3-Piperidyl)Methanamine
CAS No.	1185749-68-1
Molecular Formula	C13H19FN2
Molecular Weight	222.30 g/mol
Synonyms	1-Benzyl-3-fluoro-3-(aminomethyl)piperidine; 3-Fluoro-3-(aminomethyl)-1-benzylpiperidine; (3-Fluoro-1-benzylpiperidin-3-yl)methanamine; 1-Benzyl-3-fluoro-3-piperidinemethanamine; 1185749-68-1; (1-Benzyl-3-fluoro-3-piperidyl)methanamine; 3-(Aminomethyl)-1-benzyl-3-fluoropiperidine
EINECS	Contact for details

Quality Control

Every batch of (1-Benzyl-3-Fluoro-3-Piperidyl)Methanamine is produced under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, impurity profiles, and physical characteristics. Our commitment to cGMP principles and ISO-aligned processes guarantees batch-to-batch consistency and traceability for demanding R&D and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccator for long-term storage to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.