Description

1-Tosyl-5-Azaindole-3-Boronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and building block for organic synthesis. This compound matters for its crucial role in facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical and agrochemical industries for the research and development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those containing azaindole and biaryl motifs.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the formation of carbon-carbon bonds to create diverse compound libraries for high-throughput screening and lead optimization.
• Medicinal Chemistry Research: Used in the discovery and development of new therapeutic agents targeting various diseases.
• Agrochemical Synthesis: Serves as a precursor in the creation of novel pesticides and herbicides with improved efficacy.
• Material Science: Potential use in the development of organic electronic materials and ligands for catalysis.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services.

Basic Information

Product Name	1-Tosyl-5-Azaindole-3-Boronic Acid Pinacol Ester
CAS No.	1185427-30-8
Molecular Formula	C20H21BN2O4S
Molecular Weight	396.27 g/mol
Synonyms	1-[(4-Methylphenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridine-3-boronic acid, pinacol ester; 5-Azaindole-3-boronic acid pinacol ester, 1-tosyl-; 1-Tosyl-1H-pyrrolo[2,3-b]pyridine-3-boronic acid pinacol ester; 1-Tos-5-Aza-indole-3-Bpin; 1-Tosyl-5-azaindol-3-ylboronic acid pinacol ester; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-tosyl-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 1-Tosyl-5-Azaindole-3-Boronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opened for prolonged periods to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.