Description

Ethyl 2-Cyclopropyl-2-Hydroxyacetate is a high-value chiral building block and synthetic intermediate of significant interest in advanced organic synthesis. Its unique structure, featuring both a cyclopropyl ring and a β-hydroxy ester moiety, makes it a versatile precursor for constructing complex molecular architectures. This compound is particularly valuable for pharmaceutical R&D and fine chemical manufacturing, where it is used to introduce functionalized cyclopropane units into target molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of active pharmaceutical ingredients (APIs), especially in antiviral, antifungal, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Building block for creating novel pesticides and herbicides that leverage the metabolic stability of the cyclopropane group.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands for asymmetric catalysis and organometallic complexes.
• Flavor and Fragrance Industry: Intermediate for synthesizing esters and lactones with complex, nuanced olfactory profiles.
• Material Science Research: Monomer or cross-linking agent in the development of specialty polymers with tailored properties.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry, including ring-opening and stereoselective transformations.

Basic Information

Product Name	Ethyl 2-Cyclopropyl-2-Hydroxyacetate
CAS No.	1185387-66-9
Molecular Formula	C7H12O3
Molecular Weight	144.17 g/mol
Synonyms	Ethyl 2-Cyclopropyl-2-Hydroxyacetate; 2-Cyclopropyl-2-hydroxyacetic acid ethyl ester; Ethyl α-Cyclopropyl-α-hydroxyacetate; Ethyl (2-Hydroxy-2-cyclopropyl)acetate; 2-Hydroxy-2-cyclopropylacetic Acid Ethyl Ester; Ethyl 2-Hydroxy-2-cyclopropylacetate; (2-Cyclopropyl-2-hydroxy-acetic acid) ethyl ester; Ethyl O-Cyclopropylglycolate
EINECS	Contact for details

Quality Control

Our Ethyl 2-Cyclopropyl-2-Hydroxyacetate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements of our global B2B clients in research and manufacturing. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, enantiomeric excess (if applicable), and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). The product may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for high-purity grades.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.