Description

3-[4-(Trifluoromethyl)Phenoxy]Benzylamine Hcl is a high-purity organic building block featuring a benzylamine core substituted with a trifluoromethylphenoxy group. This compound is valued for its role as a versatile intermediate in advanced organic synthesis, particularly where the introduction of a fluorine-containing aromatic moiety is required. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or requiring metabolic stability enhancement.
• Agrochemical Research: Used in developing novel herbicides, fungicides, or insecticides where the trifluoromethyl group can improve bioactivity and environmental persistence.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic processes or metal-organic frameworks (MOFs).
• Material Science: Intermediate for synthesizing advanced polymers or liquid crystals with specific optical or electronic properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes and scale-up projects.

Basic Information

Product Name	3-[4-(Trifluoromethyl)Phenoxy]Benzylamine Hcl
CAS No.	1185096-87-0
Molecular Formula	C14H12ClF3NO
Molecular Weight	302.70 g/mol
Synonyms	1-[[4-(Trifluoromethyl)phenoxy]methyl]benzenamine hydrochloride; Benzenemethanamine, 4-[(α,α,α-trifluoro-p-tolyl)oxy]-, hydrochloride; 3-((4-(Trifluoromethyl)phenoxy)methyl)aniline hydrochloride; 4-[(α,α,α-Trifluoro-p-tolyl)oxy]benzenemethanamine hydrochloride; 3-[4-(Trifluoromethyl)phenoxy]phenylmethanamine hydrochloride
EINECS	Contact for details

Quality Control

Our 3-[4-(Trifluoromethyl)Phenoxy]Benzylamine Hcl is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a Certificate of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.