Description

Bdcs, Silylation Reagent, Acroseal CAS NO 1185092-02-7 is a specialized organosilicon compound designed for efficient silylation reactions. This reagent is critical for protecting sensitive functional groups, such as hydroxyls, during complex synthetic sequences in pharmaceutical and fine chemical manufacturing. It is an essential tool for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, reliable intermediates for scalable synthesis.

Application

• Pharmaceutical Intermediate Synthesis: Used as a key protecting group agent in the multi-step synthesis of active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Protects hydroxyl groups on amino acid side chains (e.g., serine, threonine, tyrosine) during solid-phase and solution-phase peptide synthesis.
• Natural Product Derivatization: Facilitates the isolation and structural modification of complex natural products by selectively silylating hydroxyl groups.
• Analytical Chemistry: Employed as a derivatization agent to enhance the volatility and detectability of polar compounds in Gas Chromatography (GC) and GC-Mass Spectrometry (GC-MS).
• Polymer & Material Science: Serves as a monomer or surface-modifying agent in the development of silicone-based polymers and hybrid materials.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents where selective protection of functional groups is required.

Basic Information

Product Name	Bdcs, Silylation Reagent, Acroseal
CAS No.	1185092-02-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Acroseal Bdcs; Bdcs Silylation Reagent; tert-Butyldimethylchlorosilane derivative; TBDMS-Cl derivative; Silylating agent 1185092-02-7; Organosilane protecting reagent; Hydroxyl protecting group reagent; Silicon-based derivatization agent
EINECS	Contact for details

Quality Control

Our Bdcs, Silylation Reagent, Acroseal is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Purity (HPLC/GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.