Description

Flumequine-13C3 is a stable isotope-labeled analog of the veterinary antibiotic flumequine, specifically enriched with carbon-13 at three positions. This compound is an essential internal standard for the precise and accurate quantification of flumequine in complex matrices using advanced analytical techniques. It is primarily required by analytical laboratories, contract research organizations (CROs), and pharmaceutical companies engaged in veterinary drug residue analysis, pharmacokinetic studies, and quality control of animal-derived food products to ensure compliance with global safety regulations.

Application

• Internal Standard for LC-MS/MS: Serves as a critical reference standard in liquid chromatography-tandem mass spectrometry (LC-MS/MS) for the quantification of flumequine in biological samples, feed, and food products like meat, milk, and eggs.
• Veterinary Drug Residue Testing: Enables reliable monitoring and confirmation of flumequine residues to comply with Maximum Residue Limits (MRLs) set by regulatory bodies (e.g., FDA, EMA, USDA).
• Pharmacokinetic and Metabolism Studies: Used in research to study the absorption, distribution, metabolism, and excretion (ADME) profile of flumequine in animals.
• Method Development and Validation: Essential for developing, optimizing, and validating robust analytical methods in accordance with guidelines like ISO 17025.
• Quality Control and Assurance: Employed in the quality control laboratories of pharmaceutical manufacturers to ensure the potency and purity of flumequine-based formulations.
• Environmental Analysis: Facilitates the trace analysis of flumequine in environmental water samples to assess ecological impact from veterinary use.

Basic Information

Product Name	Flumequine-13C3
CAS No.	1185049-09-5
Molecular Formula	C13H3^13C3FNO3
Molecular Weight	~264.19 (based on ^13C enrichment)
Synonyms	9-Fluoro-6,7-dihydro-5-methyl-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic acid-13C3; 13C3-Flumequine; [13C3]-Flumequine; Flumequine (13C3); Flumequine-13C3 isotope; 9-Fluoro-5-methyl-1-oxo-6,7-dihydro-1H,5H-benzo[ij]quinolizine-2-carboxylic-13C3 acid; FLU-13C3
EINECS	Contact for details

Quality Control

Every batch of Flumequine-13C3 is manufactured and analyzed under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the high standards required for quantitative mass spectrometry. This includes verification of chemical purity, isotopic enrichment (typically ≥99 atom % ^13C), and absence of interfering impurities. A detailed Certificate of Analysis (COA) is supplied with each lot, containing results from NMR, HPLC, and MS analysis.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, keep the product under inert atmosphere at -20°C to ensure maximum stability of the labeled compound.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity (^13C)	≥99 atom %
Chemical Purity	≥95%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.