Description

2-Methoxy-4-Nitrophenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and fine chemical synthesis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of biaryl compounds, a common motif in active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate Synthesis: Used in the research and development of novel drug candidates, particularly those containing complex aromatic systems.
• Agrochemical Product Development: Employed in creating new herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand and Catalyst Preparation: Acts as a precursor for synthesizing specialized ligands used in homogeneous catalysis.
• Material Science Research: Facilitates the development of organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Biology Probes: Useful in synthesizing molecular probes for studying biological processes and target engagement.

Basic Information

Product Name	2-Methoxy-4-Nitrophenylboronic Acid Pinacol Ester
CAS No.	1185019-97-9
Molecular Formula	C₁₃H₁₈BNO₅
Molecular Weight	279.10 g/mol
Synonyms	2-Methoxy-4-nitrophenylboronic acid pinacol ester; (2-Methoxy-4-nitrophenyl)boronic acid pinacol ester; 4-Nitro-2-methoxyphenylboronic acid pinacol ester; 2-Methoxy-4-nitrobenzeneboronic acid pinacol ester; Pinacol (2-Methoxy-4-nitrophenyl)boronate; B-(2-Methoxy-4-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 2-Methoxy-4-Nitrophenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity. Certificates of Analysis (COA) with full traceability are provided to guarantee consistent quality and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.