Description

2-(tert-Butyl)Nicotinaldehyde is a specialized pyridine derivative aldehyde that serves as a crucial building block in advanced organic synthesis. Its molecular structure, featuring both a sterically hindered tert-butyl group and a reactive aldehyde functionality, makes it a valuable precursor for creating complex heterocyclic compounds and fine chemicals. This high-purity intermediate is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting nicotinic receptors or requiring functionalized pyridine cores.
• Agrochemical Synthesis: Used in the research and development of new pesticides, herbicides, and plant growth regulators where the tert-butyl-pyridine scaffold imparts specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating sophisticated chiral or non-chiral ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers, due to its electron-deficient pyridine ring.
• Fine Chemical Production: A versatile starting material for manufacturing specialty chemicals, dyes, and photoinitiators.

Basic Information

Product Name	2-(tert-Butyl)Nicotinaldehyde
CAS No.	1184658-38-5
Molecular Formula	C10H13NO
Molecular Weight	163.22 g/mol
Synonyms	2-(1,1-Dimethylethyl)pyridine-3-carboxaldehyde; 3-Formyl-2-tert-butylpyridine; 2-tert-Butyl-3-pyridinecarboxaldehyde; 2-(tert-Butyl)-3-pyridinecarbaldehyde; Nicotinaldehyde, 2-(1,1-dimethylethyl)-; 2-tert-Butylnicotinaldehyde; 2-(tert-Butyl)nicotinic aldehyde
EINECS	Contact for details

Quality Control

Every batch of 2-(tert-Butyl)Nicotinaldehyde is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming identity, purity, and impurity profiles. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade synthesis, supporting reliable and reproducible results in your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. This compound is easily oxidized (store under inert atmosphere).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.