Description

3-Formyl-4-Nitrophenyl Boronicacid Pinacol Ester is a high-purity, multifunctional boronic ester building block essential for modern synthetic chemistry. Its unique structure, featuring both a formyl and a nitro group, makes it a versatile intermediate for constructing complex molecules via Suzuki-Miyaura cross-coupling and other palladium-catalyzed reactions. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring biaryl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that leverage its boronic ester functionality for structural diversification.
• Material Science: Serves as a building block for creating organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where its conjugated system is valuable.
• Chemical Biology & Proteomics: Employed in the development of molecular probes and sensors that target biomolecules, utilizing the boronic acid ester's affinity for diols.
• Cross-Coupling Reactions: A critical reagent in Suzuki-Miyaura cross-coupling reactions to form carbon-carbon bonds between aromatic rings, a fundamental transformation in medicinal chemistry.
• Ligand & Catalyst Development: Used to synthesize novel bidentate or tridentate ligands for transition metal catalysis.

Basic Information

Product Name	3-Formyl-4-Nitrophenyl Boronicacid Pinacol Ester
CAS No.	1184259-08-2
Molecular Formula	C₁₃H₁₆BNO₅
Molecular Weight	277.08 g/mol
Synonyms	(3-Formyl-4-nitrophenyl)boronic acid pinacol ester; 4-Nitro-3-formylbenzeneboronic acid pinacol ester; Pinacol (3-formyl-4-nitrophenyl)boronate; (3-Formyl-4-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Formyl-4-nitrobenzeneboronic acid pinacol ester; Boronic acid, B-(3-formyl-4-nitrophenyl)-, 1,1-dimethylethyl ester (9CI); 1184259-08-2
EINECS	Contact for details

Quality Control

Our 3-Formyl-4-Nitrophenyl Boronicacid Pinacol Ester is manufactured under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our production adheres to cGMP principles where applicable, ensuring consistency and traceability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light). Keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.