Description

2'-Acetyl-4-Fluoro-3-Methylbiphenyl is a high-purity, advanced pharmaceutical intermediate characterized by its specific biphenyl structure with acetyl and fluorine substituents. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), where its precise molecular architecture serves as a key building block. It is primarily required by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel small-molecule drugs, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production pathway for advanced herbicides and fungicides, leveraging the stability imparted by the fluorinated biphenyl core.
• Material Science Research: Serves as a monomer or building block for developing specialty polymers and liquid crystals with tailored electronic properties.
• Organic Synthesis & Catalysis: Employed in academic and industrial R&D for constructing complex molecular architectures and studying novel catalytic reactions.

Basic Information

Product Name	2'-Acetyl-4-Fluoro-3-Methylbiphenyl
CAS No.	1184000-23-4
Molecular Formula	C15H13FO
Molecular Weight	228.26 g/mol
Synonyms	1-(2'-Biphenylyl)-2-fluoro-5-methylacetophenone; 1-[2-(4-Fluoro-3-methylphenyl)phenyl]ethanone; 4'-Fluoro-3'-methyl-2-acetylbiphenyl; 2-Acetyl-4-fluoro-3-methylbiphenyl; [1,1'-Biphenyl]-2-ethanone, 4'-fluoro-3'-methyl-
EINECS	Contact for details

Quality Control

Our 2'-Acetyl-4-Fluoro-3-Methylbiphenyl is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.