Description

1-(3-Fluorophenyl)-3-Methylbutan-1-Amine is a specialized fluorinated amine building block of significant interest in advanced organic synthesis. This compound matters for its role as a key chiral intermediate in the development of active pharmaceutical ingredients (APIs) and other high-value fine chemicals. Pharmaceutical researchers, agrochemical developers, and specialty chemical manufacturers need this precise chemical scaffold to introduce specific fluorophenyl and branched alkyl amine functionalities into target molecules, enabling the fine-tuning of biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides where the fluorophenyl moiety enhances bioavailability and target specificity.
• Ligand and Catalyst Development: Serves as a building block for chiral ligands used in asymmetric catalysis, crucial for producing enantiomerically pure compounds.
• Material Science Research: Employed in the creation of specialty monomers and functional polymers with tailored properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and receptor interactions.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring a specific fluorinated amine backbone.

Basic Information

Item	Details
Product Name	1-(3-Fluorophenyl)-3-Methylbutan-1-Amine
CAS No.	1183422-59-4
Molecular Formula	C11H16FN
Molecular Weight	181.25 g/mol
Synonyms	3-Fluoro-α-isobutylbenzylamine; 1-(3-Fluorophenyl)-3-methylbutylamine; (3-Fluorophenyl)(3-methylbutyl)amine; 3-Fluoro-α-isobutylbenzylamine; 1-Amino-1-(3-fluorophenyl)-3-methylbutane; m-Fluoro-α-isobutylbenzylamine; 3-Fluoro-α-(isobutyl)benzylamine
EINECS	Contact for details

Quality Control

Our 1-(3-Fluorophenyl)-3-Methylbutan-1-Amine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability, consistency, and reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Specific Rotation (if chiral)	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.