Description

2-(4-Chlorophenyl)-1-(2-Fluorophenyl)Ethanone is a high-purity fluorinated and chlorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its unique bifunctional structure, featuring both electron-withdrawing chloro and fluoro substituents on separate aromatic rings, makes it a versatile precursor for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used as a building block for creating advanced herbicides, fungicides, and insecticides, leveraging its halogenated aromatic system.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for transition metal catalysis and organocatalysts.
• Material Science Research: Acts as a monomer or precursor for synthesizing specialty polymers and advanced organic electronic materials.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in chemical manufacturing.
• Academic & Industrial R&D: A valuable reagent for methodological studies in cross-coupling reactions and other fluorination/functionalization chemistry.

Basic Information

Product Name	2-(4-Chlorophenyl)-1-(2-Fluorophenyl)Ethanone
CAS No.	1183199-32-7
Molecular Formula	C14H10ClFO
Molecular Weight	248.68 g/mol
Synonyms	1-(2-Fluorophenyl)-2-(4-chlorophenyl)ethanone; 2-(4-Chlorophenyl)-1-(2-fluorophenyl)ethan-1-one; 2-Fluoro-α-(4-chlorobenzyl)acetophenone; 4'-Chloro-2-fluorodesoxybenzoin; (4-Chlorophenyl)(2-fluorophenyl)methanone, methylene-; Ethanone, 2-(4-chlorophenyl)-1-(2-fluorophenyl)-
EINECS	Contact for details

Quality Control

Our 2-(4-Chlorophenyl)-1-(2-Fluorophenyl)Ethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting critical parameters such as assay and impurity profiles. Our quality commitment supports applications requiring high reliability, from research to scale-up development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent contamination and moisture absorption. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.