Description

1-(2-Bromophenyl)-3-Methylbutan-2-One is a specialized brominated aromatic ketone building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a bromine substituent and a branched alkyl ketone chain, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and pharmaceutical development companies engaged in the creation of novel active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders or anti-inflammatory agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, where the bromophenyl moiety can contribute to biological activity.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing specialized ligands used in asymmetric catalysis or metal-organic frameworks (MOFs).
• Material Science: Employed in the research of organic semiconductors, liquid crystals, or photoactive polymers due to its conjugated aromatic system.
• Chemical Biology Probes: Useful for creating tagged molecules or probes for studying biological pathways and protein interactions.
• Custom Synthesis and Scale-Up: Provided for contract research organizations (CROs) and CDMOs requiring reliable, high-purity building blocks for client projects.

Basic Information

Product Name	1-(2-Bromophenyl)-3-Methylbutan-2-One
CAS No.	1183050-47-6
Molecular Formula	C11H13BrO
Molecular Weight	241.12 g/mol
Synonyms	2'-Bromoisobutyrophenone; 1-(2-Bromophenyl)-3-methyl-2-butanone; 2-Bromo-α-isobutyrylbenzene; 2-Bromophenyl isopropyl ketone; α-Methyl-2-bromopropiophenone; 2-Bromo-α,α-dimethylacetophenone; (2-Bromophenyl)(isopropyl)methanone
EINECS	Contact for details

Quality Control

Our production of 1-(2-Bromophenyl)-3-Methylbutan-2-One adheres to stringent quality management protocols. Each batch is characterized and tested using advanced analytical techniques including GC, HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.