Description

3-(3-Chloro-4-Fluorophenyl)Benzaldehyde is a high-purity, halogenated aromatic aldehyde building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both chloro and fluoro substituents, makes it a versatile and valuable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, receptor modulators, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, where the chloro-fluorophenyl moiety can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as monomers for conjugated polymers or molecular components for OLEDs, due to its electron-withdrawing character.
• Custom Chemical Synthesis: A fundamental building block for contract research organizations (CROs) and fine chemical manufacturers producing bespoke compounds for client projects.

Basic Information

Product Name	3-(3-Chloro-4-Fluorophenyl)Benzaldehyde
CAS No.	1181381-74-7
Molecular Formula	C13H8ClFO
Molecular Weight	234.65 g/mol
Synonyms	3-(3-Chloro-4-fluorophenyl)benzaldehyde; [1,1'-Biphenyl]-3-carboxaldehyde, 3'-chloro-4'-fluoro-; 3'-Chloro-4'-fluoro-[1,1'-biphenyl]-3-carboxaldehyde; 3-(3-Chloro-4-fluorophenyl)benzaldehyde; 3-Chloro-4-fluorobiphenyl-3-carboxaldehyde
EINECS	Contact for details

Quality Control

Every batch of 3-(3-Chloro-4-Fluorophenyl)Benzaldehyde is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure consistency and high purity. Our standard quality commitment includes providing a detailed Certificate of Analysis (COA) with each shipment, which reports key parameters such as assay (HPLC), identity confirmation, and impurity profiles. We adhere to cGMP principles where applicable to support our clients in regulated development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or after opening to maintain purity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.