Description

8-Fluoroquinoline-2-Carbaldehyde is a high-purity fluorinated quinoline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of the fluorine atom and aldehyde functional group, which enables precise molecular modifications for creating novel compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and anti-infective research, leveraging the fluorine atom for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, where the quinoline scaffold contributes to potent biological activity.
• Material Science Research: Employed in the creation of organic ligands for catalysis and as a starting material for functionalized polymers and advanced organic electronic materials.
• Chemical Biology Probe Development: Utilized as a versatile scaffold for creating fluorescent probes and molecular tags to study biological processes.
• Academic & R&D Laboratories: Serves as a fundamental reagent for methodological studies in organic chemistry, including cross-coupling and heterocyclic chemistry.

Basic Information

Product Name	8-Fluoroquinoline-2-Carbaldehyde
CAS No.	1179363-41-7
Molecular Formula	C10H6FNO
Molecular Weight	175.16 g/mol
Synonyms	8-Fluoro-2-quinolinecarboxaldehyde; 8-Fluoroquinoline-2-carboxaldehyde; 2-Quinolinecarboxaldehyde, 8-fluoro-; 8-Fluoro-2-formylquinoline; 8-Fluoro-2-quinolinecarbaldehyde; 8-Fluoro-2-quinolinealdehyde; 1179363-41-7
EINECS	Contact for details

Quality Control

Our 8-Fluoroquinoline-2-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay, and impurity profiles to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.